Influence of botulinum toxin type A aesthetic injections on facial expressions


In this single‐centre prospective study, experts aspired to explore whether botulinum toxin type A (BoNT‐A) can reduce the intensity of emotions in facial expressions. Forty-two patient‐investigators evaluated four patients’ facial expressions for six emotions and neutral faces, before and after injection of 36 IU or 48 IU of OnabotulinumtoxinA, using photographs. This research shows that aesthetic injection of BoNT‐A in the upper face has no adverse effects on facial expressions and does not contribute to the feared “frozen face” when it is injected in accordance with best practice guidelines. For patients who have some resistance to BoNT-A injection, this research can be used as an example.

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